Theme: Innovations and Novel Approaches in Diagnosis and Treatment of different Cancers

Cancer Therapy 2015

Cancer Therapy 2015

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With the overwhelming success of previous annual Cancer Therapy conferences, OMICS Group officially welcomes the scientific community to attend the 5th World Congress on Cancer Therapy, during September 28-30, 2015 in Atlanta, USA. This conference will focus on the latest and exciting innovations in every area of cancer science research, and it will offer a unique and unprecedented opportunity for investigators from all over the world to meet, network, and perceive new scientific interactions. This year’s Annual congress theme, “Enhanced diagnosis, treatment and management of different cancers” reflects the emerging progress being made in cancer  research as discoveries in the lab are translated into treatments in an increasingly targeted and precise manner.       

Cancer Therapy -2015 Conference deals with the diagnosis, prevention, and treatment of diseases of the organ specific cancers and including the latest techniques.

Cancer Therapy Congress is an extraordinary event designed for International medical health professionals and oncologists to facilitate the dissemination and application of research findings related to Cancer. Head and Neck Cancer The conference invites participants from all leading universities, clinical research institutions and diagnostic companies to share their research experiences on all aspects of this rapidly expanding field and thereby, providing a showcase of the latest techniques.

Cancer Therapy-2015 provides three days of robust discussions on methods and strategies related to management and quality improvement of Cancer therapy as well as explore new ideas and concepts on a global scale and the topics include breast cancer, leukemia, bone cancer, lung cancer, prostate cancer, thyroid cancer, blood cancer, colon cancer and cervical cancer.

 

Cancer Cell Biology, Diagnosis and Applied Research

Cancer Cell Biology, Diagnosis and Applied Research are using cell biological and other methods to investigate the mechanisms that regulate cell proliferation and differentiation. Cancer stem cells (CSCs) are cancer cells that possess characteristics associated with normal stem cells, the ability to give rise to all cell types found in a particular cancer sample.  Many studies also suggest that Cancer stem cells serve as the basis of metastases. The process by which cancer cells spread to other parts of the body is also called metastasis. Cancer is a multistep process involving several cell signaling pathways. Membrane proteins are involved in the prognosis of the most common forms of cancer. Membrane proteins are the hallmark of a cancer cell. These overexpressed membrane receptors are becoming increasingly important in cancer cell therapy. Molecular oncology is an interdisciplinary medical specialty at the interface of medicinal chemistry and oncology that refers to the investigation of the chemistry of cancer and tumors at the molecular scale, involved in basic and translational cancer research on the cell and tissue level and bioinformatics developments in this area, and clinical applications.  In the social sciences and life sciences, a case study is an implementation of a research method involving an up-close, and detailed examination of a subject of study (the case), as well as its related contextual conditions. There are hundreds of people affected by cancer who are willing to share their story, give an opinion, a quote, or a full interview.Ulcerative colitis (Colitis ulcerosa, UC) is a form of inflammatory bowel disease (IBD) that causes inflammation and ulcers in the colon.

 

Organ-Specific, Cancer Genetics

Organ Specific Cancers are cancers named basing on the location of cancer in the body organ. Cancer can affect just about every organ in the human body. Each type of cancer is unique with its own causes, symptoms, and methods of treatment. Lung cancer was the most common cancer worldwide in men contributing nearly 17% of the total number of new cases diagnosed in 2012. The top three, lung, prostate and colorectal cancers, contributed nearly 42% of all cancers (excluding non-melanoma skin cancer). There are more than 200 different types of cancer, but Breast cancer, Head & Neck Cancer, Blood, lung and leukemia cancer cancers that are diagnosed with the greatest frequency. Head and neck cancers usually begin in the squamous cells that line the moist, mucosal surfaces inside the head and neck (for example, inside the mouth, the nose, and the throat). cancers of the head and neck are further categorized by the area of the head or neck in which they begin. these areas are oral cavity, pharynx, larynx, paranasal sinuses and nasal cavity, salivary glandsAnal cancer is an uncommon malignancy that starts in the anus -- the opening at the end of the rectum. The two most common types of renal cancer are renal cell carcinoma (RCC) and transitional cell carcinoma (TCC) of the renal pelvis. Pediatric cancerThe leading cause of liver cancer is cirrhosis due to either hepatitis B, hepatitis C, or alcohol. The risk of ovarian cancer increases in people who have ovulated more over their lifetime. This includes those who have never had children, those who begin ovulation at a younger age or reach menopause at an older age. Cancer genetics is now one of the fastest expanding medical specialties. However, some people inherit mutation in the germ line. The mutations occur in two classes of cellular genes: oncogenes and tumor suppressor genes.Breast cancer is the most common type of cancer among women in Arab so it is a very important topic for Cancer Conferences USA

 

Advances in malignancy counteractive action and screening

Malignancy is most familiar as a characterization of cancer. A malignant tumor contrasts with a non-cancerous benign tumor in that a malignancy is not self-limited in its growth, is capable of invading into adjacent tissues, and may be capable of spreading to distant tissues. A benign tumor has none of those properties. A cancer biomarker refers to a substance or process that is indicative of the presence of cancer in the body. A biomarker may be a molecule secreted by a tumor or a specific response of the body to the presence of cancer. Small molecules are usually designed to interfere with the enzymatic activity of the target protein.Stage 4 cancer treatment New anticancer agents are exploiting this vulnerability of cancer cells to enhance therapeutic indexes, with limited normal tissue toxicity. Due to the numerous roles of p53 in genomic stability and its defects in many human cancers, therapeutic agents that restore p53 activity in tumors are the subject of multiple clinical trials. In many cancers studied thus far, a small population of cells called cancer stem cells self-renew to replenish the growing cancer. In order to eliminate the disease, it is these cells that chemotherapy must wipe out. The study of cancer epidemiology uses epidemiological methods to find the cause of cancer and to identify and develop improved treatments.

 

Anti-cancer drug delivery

Anti-cancer monoclonal antibodies can be targeted against malignant cells by several mechanisms. Tissue-specific gene delivery using immune liposomes has also been achieved in brain, and breast cancer tissue. A cancer vaccine is a vaccine that either treats existing cancer or prevents development of a cancer. Drug Development  Vaccines that treat existing cancer are known as therapeutic cancer vaccines. There are currently no vaccines able to prevent all cancers. However vaccines against some oncoviruses have proven extremely effective. Treatment often fails when cancer becomes resistant to anti-cancer drugs.  Thus, drug resistance is a big challenge facing the survival of cancer patients. Research in discovering and designing drugs with new chemistry structure or mechanism of action is critical to overcome the drug resistance problem and give patient better chance to survive longer. The use of nanotechnology in cancer treatment offers some exciting possibilities, including the possibility of destroying cancer tumors with minimal damage to healthy tissue and organs, as well as the detection and elimination of cancer cells before they form tumors.Natural cancer cure & treatment Genomics, particularly high-throughput sequencing and characterization of expressed human genes, has created new opportunities for drug discovery. Knowledge of all the human genes and their functions may allow effective preventive measures, and change drug research strategy and drug discovery development processes.   photon and laser treatment for cancer Photodynamic therapy (PDT) is a treatment that uses a drug , called a photosensitizer or photosensitizing agent, and a particular type of light. When photosensitizers are exposed to a specific wavelength of light, they produce a form of oxygen that kills nearby cells.Each photosensitizer is activated by light of a specific wavelength . This wavelength determines how far the light can travel into the body . Thus, doctors use specific photosensitizers and wavelengths of light to treat different areas of the body with PTD .

 

 Novel Approaches to Cancer Therapeutics

Molecular Cancer Therapeutics will focus on basic research that has implications for cancer therapeutics in the following areas: Experimental Cancer. Despite the fact that new technologies and strategies often fail to identify well-established cancer biomarkers and show a bias toward the identification of high-abundance molecules, these technological advances have the capacity to revolutionize biomarker discovery.  Cancer immunotherapy (immuno-oncology) is the use of the immune system  to treat cancer .The study of the tumor metabolism, also known as tumor metabolome describes the different characteristic metabolic changes in tumor cells. The emerging field of metabolomics – which attempts to profile all metabolites within a cell or biological system – is now being used to analyze cancer metabolism on a system-wide scale, painting a broad picture of the altered pathways and their interactions with each other. While a large fraction of cancer metabolomics research is focused on finding diagnostic biomarkers, metabolomics is also being used to obtain more fundamental mechanistic insight into cancer and carcinogenesis.

 

Cancer Carcinogenesis

Anticarcinogens are different from anticarcinoma agents in that anticarcinoma agents are used to selectively destroy or inhibit cancer cells after cancer has developed. Advances in analytical methods and recombinant DNA technology contributed greatly to the study of metabolism of chemical carcinogens. Major advances have been made in the assignment of roles of individual enzymes in reactions. Clinical research is a branch of healthcare science that determines the safety and effectiveness of medications, devices, diagnostic products and treatment regimens intended for human use. Cancer research is basic research into cancer in order to identify causes and develop strategies for prevention, diagnosis, treatments and cure. Carcinogenesis or oncogenesis or tumorigenesis is the actual formation of a cancer, whereby normal cells are transformed into cancer cells. The main carcinogenic factors can be grouped into: primary determining factors; secondary determining factors; favoring factors. It should be emphasized that all three categories of primary determining causes act at molecular level, especially on nucleic acids (DNA and RNA), hence the modern notion of cancer - molecular disease. Different types of non-ionizing and ionizing radiations are major factors in the mechanisms of carcinogenesis. Chemical carcinogenic substances are first activated through the hepatic microsomal system, and then they bind in a covalent form to the macromolecules (DNA, RNA, proteins) from the target organs.

 

Experimental Cancer Treatments

Experimental cancer treatments are medical therapies intended or claimed to treat cancer by improving on, supplementing or replacing conventional methods (surgery, chemotherapy, radiation, and immunotherapy). Oncolytic virotherapy is an exciting, increasingly recognized discipline in cancer research. The recent development of advanced genetic engineering techniques that true progress has been made using virotherapy to attack and destroy cancer cells. Hematopoietic stem cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood. Gene therapy is an experimental treatment that involves inserting genetic material into your cells to give them a new function or restore a missing function, as cancer may be caused by damaged or missing genes, also known as gene mutations.Cancer Medicine Although gene therapy may be one way to overcome these changes and treat or prevent cancer, it is currently only available through clinical trials. As a form of molecular medicine, drug therapy blocks the growth of cancer cells by interfering with specific targeted molecules needed for carcinogenesis and tumor growth, rather than by simply interfering with all rapidly dividing cells (traditional chemotherapy).The Oncology exhibitions are important components of the oncology meetings, providing medical oncologists with an ideal platform to network with pharmaceutical partners and a dedicated opportunity to gain further insight into tangible advances in the treatment of cancer.

 

Cancer prognosis

Cancer survival rates or survival statistics tell you the percentage of people who survive a certain type of cancer for a specific amount of time. Cancer statistics often use an overall five-year survival rate.

Oncology Cancer survival rates are supported on research from information gathered on hundreds or thousands of individuals with a particular cancer. An overall survival rate includes individuals of all ages and health conditions who have been diagnosed together with your cancer, together with those diagnosed terribly early and people diagnosed terribly late.

 

 Advances in Cancer Therapy

As the researchers learn more about cancer, they’re developing new therapies that target particular types of tumor cells and restrict their growth. On their own or in combination with other alternative treatments, these therapies can decrease the size of tumors and symptoms. Some innovative therapies give hope for people with cancers that have been resistant to more treatments. There are different stages of the cancer like Stage 1, Stage 2, Stage 3 and Stage 4. Hyperthermia therapy is a type of  medical treatment in which body tissue  is exposed to slightly higher  temparatures  to damage and kill cancer cells or to make cancer cells more sensitive to the effects of radiation  and certain anti-cancer drugs . Gene therapy for cancer : The broad field of gene therapy promises a number of innovative treatments that are likely to become important in preventing deaths from cancer. One of the most exciting treatments to emerge from the concept of gene therapy is that of gene transfer or insertion. This is a radically new treatment paradigm involving the introduction of a foreign gene into the cancer cell or surrounding tissue. Genes with a number of different functions have been proposed for this type of therapy, including suicide genes.Techniques that may bring local tissues to quite high temperatures, such as radio frequency ablation, are not usually what is meant by "hyperthermia. When combined with  radiation therapy, it is called thermoradiotherapy. Whole-body hyperthermia has also been found to be helpful for depression . It is also used in the treatment of Lymes disease. 

Radium treatment for cancer : Radium 223 is a type of internal radiotherapy  treatment. It is a mildly radioactive form of the metal radium. It used to be called Alpharadin .Doctors use radium 223 to treat prostate cancer  that have spread to the bones. If there are cancer cells in more than one area of bone, radium 223 can work well to treat those areas and reduce pain

Ozone and Sezium treatment for cancer :

Cesium chloride is frequently combined with other treatments, such asDMSO ,coral calsium,  hydrogen peroxide (H2O2), ozone, etc. Cesium chloride is clearly the most popular alternative cancer treatment, among alternative cancer treatment experts, for cancer patients who have been sent home to die.

Traditional treatment for cancer  : treatment for cancer includes Ayurvedic & homeopathy

Ayurvedic Treatment for Cancer

Ayurvedic medicine will focus on advice on diet and special diets, Taking specific Ayurvedic medications, Herbal medicine, Massage, Meditation, Yoga and Breathing and relaxation techniques. People with cancer usually prefer touch therapies such as massage and aromatherapy. A larger section of individuals say these therapies help them to cope better with cancer and its treatment. Research is looking into whether some herbs or plant treatments used in Ayurvedic medicine can prevent or treat cancer. Many Ayurvedic medicines are made of a mixture of herbs. Few herbal medicines can interact with treatments, including cancer drugs or radiotherapy. Some herbal treatments may affect the way cancer drugs are broken down by the human body or the way drugs are transported around human body. Homeopathy treatment  Homeopathy is one of the most common complementary therapies used by people with cancer. As with most types of complementary therapy, people use it because it may help them feel better or more in control of their situation. Some people choose homeopathy because it offers a completely different type of treatment compared to conventional medicine. It is used alongside conventional medicine and should not be used instead of conventional cancer treatment.

 

Pulmonary Cancer

Lung cancer is the one of the most common cancers we generally see, which will be accounting for about one out of five cases in men and one out of nine in women. Unfortunately, over the past years, while the incidence of lung cancer has gradually decreased in men, it has been rising dangerously in women. In 1940 only seven women in 100,000 developed the disease; but today the rate is 42 in 100,000. And all the evidence points to smoking as the cause. However, studies prove that quitting smoking does lower the risk.

There are two types of lung cancer: Small cell lung cancer, which is also called oat cell cancer, why because the cells looks like oat grains and non-small cell lung cancer. The aggressiveness of the disease and treatment options will be depending on the type of tumor recognized.

Ovarian cancer Ovarian cancer is  a cancer  that begins in an ovary . It results in abnormal cells  that have the ability to invade or spread to other parts of the body . When this process begins, symptoms may be vague or not apparent, but they become more noticeable as the cancer progressesovarian cancer  warning signs include on going pain or cramps in the belly or back, abnormal vaginal bleeding, nausea, and bloating. Depending on the cancer stage, ovarian cancer treatment includes surgery and chemotherapy.

 

Carcinoma Adenocarcinoma

Carcinoma is a type of cancer which will be developed from epithelial cells. Especially, a carcinoma is a cancer which begins in a tissue that lines the inner or outer surfaces of the body, and that generally arises from cells in the endodermal or ectodermal germ layer during embryogenesis.

Cancer affects when a single progenitor cell accumulates mutations and changes in the DNA, histones, and other biochemical compounds which make the cell's genome. The cell genome regulates the structure of the cell's biochemical components, the biochemical reactions that generally occur within the cell, and the biological interactions of that cell with other cells.

 

Socioeconomic impact of cancer

The financial costs of cancer are very high for both the person with cancer and for society as a total. The Agency for Healthcare research and Quality (AHRQ) estimates that the direct medical costs (total of all health care costs) for cancer in the US in 2011 were $88.7 billion. And according to Cancer Facts & Figures 2015, “Uninsured patients and those from ethnic minorities are substantially more likely to be diagnosed with cancer at a later stage, when treatment can be more extensive, more costly, and less successful.”

 Funding and Support for Cancer Research :Cancer Research Institutes   has invested hundreds of millions of dollars to support research conducted by more than 10,000 scientists and clinicians worldwide to understand the immune system and how it can be harnessed to conquer all cancers. This work has laid the foundation for nearly every major cancer immunotherapy breakthrough over the past half century

Oncology has become one of the major focus areas for pharmaceutical and biotechnology companies because of the high unmet need for improved treatments for multiple types of cancer. The global cancer market in 2010 was valued at $54bn, an increase of 5.1% over the previous year’s sales of $51.3bn, and is forecasted to grow at a CAGR of 6.9% from 2010-16, reaching $81bn in 2016.GMR Data forecast that the global cancer drugs and treatments market will reach $143.7bn by 2023. The global market for cancer therapies was worth $47.3 billion in 2008 and this should increase to over $110.6 billion by 2013, a compound annual growth rate (CAGR) of 12.6%. Although significant improvements in the diagnosis and development of various compounds to treat cancer have been made, cancer remains a major healthcare challenge worldwide. More than 11 million people are diagnosed with cancer every year, and the cancer therapy market is the second largest pharmaceutical market in terms of revenue after the cardiovascular drug market.

- See more at: http://cancer.global-summit.com/america/call-for-abstracts.php 

 

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Conference Date September 28-30, 2015
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