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5th World Congress on Cancer Therapy

Atlanta, USA

Gvozdenovic Ljiljana and Aleksandar Milovancev

Clinical Center of Vojvodina, Serbia

Title: Assessment and treatment of cancer pain: Our experience in Serbia


Biography: Gvozdenovic Ljiljana and Aleksandar Milovancev


Introduction: Aristotle wrote, “Th e aim of the wise is not to secure pleasure, but to avoid pain”. Despite signifi cant medical, pharmacological and technological advances in the area of cancer pain assessment and management, up to 90% of patients with advanced cancer experience pain signifi cant enough to require further intervention. Hospices are considered as leaders in cancer pain management. Methods: Th e Edmonton Classifi cation System for Cancer Pain (ECS-CP) is an instrument developed with the primary aim to predict response to treatment in patients with advanced cancer. It has gone through several stepwise and systematicvalidation studies, although its clinical application is still limited. In the fi rst version of the ECS-CP (1989), named the Edmonton Staging System for Cancer Pain (ESS), patients with advanced diseases were categorized into three groups with good, intermediate or poor prognosis for pain treatment. Th is depended on their scores on seven domains: mechanism of pain, incident pain, previous narcotic exposure, cognitive function, psychological distress, opioid tolerance and history of drug or alcohol abuse. Results: According to a large European study from 2008, in which Serbia participated, it is reported that pain was not adequately treated in 36% to 82.3% of patients. Cause of cancer related pain is most oft en related to the growth of the tumor, metastases, or pressure onto surrounding nerves, as well as to iatrogenic consequences of neurotoxic drugs. In 70-90% of patients in our country, cancer pain was treated with pharmacotherapy based on a triple therapy regimen defi ned by WHO. Discussion: Treatment of cancer related pain should follow a multimodal approach. Concept of total pain (physical, psychological, social and emotional aspects of the patient) needs to be respected. Evaluation of pain intensity is necessary before choosing therapy. Th is can be achieved with the use of pain classifi cation scales such as the Edmonton Classifi cation System for Cancer Pain (ECS-CP). Conclusion: In certain number of patients even intensive pharmacotherapy cannot provide adequate pain management, demanding non-pharmacologic methods of treatment. Th erefore, optimal pain management and development of standardized methods of cancer pain assessment is of utmost importance.