5th World Congress on Cancer Therapy
Gr. T. Popa University of Medicine and Pharmacy, Iasi, Romania
Title: The relevance of the cytological diagnostic in the mamary gland cancer
Biography: Ciobica Alin
Breast cancer is the second leading cause of cancer death in women, while in Estearn Europe is the most common form of diagnosed cancer. Out of the multiple possibilities of early detection of mammary neoplasia that have been elaborated, only mammography has proved to be a simple, effi cient method and of a high sensitivity, which can reach out to 90%. However, the cytological confi rmation of diagnosis allows us to perform the preoperative radiotherapy treatment or polychemioterapy; which is why we analyzed the informative value of these diagnosis methods in stage I mamary gland cancer (MGC). In this way, in the present report we demonstrated that collecting samples through fi ne-needle aspiration biopsy allows the cytological confi rmation of the diagnosis of stage I MGC in 30.7% cases. Moreover, in stage I MGC young patients under 35 years, the cytological confi rmation rate was 22.2% and was signifi cantly decreased, as compared to the cytological confi rmation rate in patients older than 35 years (37.9 %). Also, for a tumor diameter < 0.5 cm, the prevalence of cytological confi rmation was only 10.3%, while for the diameter of 0.6 – 1.0 cm the cytological confi rmation was around 40.0%. Th erefore, in order to improve the cytological diagnosis, the confi rmation rate for the tumor biopsy through the USG of the mammary glands is required. Moreover, the cytological investigation of the smear obtained by the fi rst and second puncture was instrumental in confi rming the diagnosis in 41.3% and respectively 17.4% cases. Also, the subsequent repetition of the punctures was not useful, as it helped to confi rmation of the diagnosis only in 9.3% cases. In addition, the frequency of diagnosis cytological confi rmation was depending on the tumor histopathological form and type of growth. Th us, the lowest prevalence was in the mixed forms - 12.5% cases, lobular cancer - 24.4% cases, while regarding the type of growth, for the rare forms the cytological confi rmation rate was 7.7% and 31.5% for the schiros growth type.