Call for Abstract
26th Annual Congress on Cancer Science and Targeted Therapies, will be organized around the theme “Securing the Future of Innovation in Cancer Treatment”
Cancer Therapy-2018 America is comprised of keynote and speakers sessions on latest cutting edge research designed to offer comprehensive global discussions that address current issues in Cancer Therapy-2018 America
Submit your abstract to any of the mentioned tracks.
Register now for the conference by choosing an appropriate package suitable to you.
Targeted therapy is a special type of chemotherapy involves a mechanism of differentiating between cancerous and non-cancerous cells in the body, attacking only the cancerous ones but not interfering with the normal ones. it is sometimes used alone, but most often other cancer treatments are used in combination with targeted therapy.
- Track 1-1Therapeutic Monoclonal Antibodies
- Track 1-2Small Molecule Drugs
- Track 1-3Tyrosine-kinase inhibitors
- Track 1-4Implications of Targeted Therapy
- Track 1-5Targeted Cancer Therapy & Health Economics
- Track 1-6Hormone Therapies
Cancer immunotherapy (Immuno-oncology or Immunooncology) is the use of the immune system to treat cancer. Immunotherapies can be categorized as active, passive or hybrid (active and passive). These approaches exploit the fact that cancer cells often have molecules on their surface that can be detected by the immune system, known as tumour-associated antigens (TAAs); they are often proteins or other macromolecules (e.g. carbohydrates). Active immunotherapy directs the immune system to attack tumor cells by targeting TAAs. Passive immunotherapies enhance existing anti-tumor responses and include the use of monoclonal antibodies, lymphocytes and cytokines.
- Track 2-1Nanosystems
- Track 2-2Targeted delivery
- Track 2-3Cell tracking
- Track 2-4Immunotherapy
- Track 2-5Tumor biology
- Track 2-6Cancer vaccines
Cancer epigenetics is the study of epigenetic modifications to the genome of cancer cells that do not involve a change in the nucleotide sequence. Epigenetic alterations are as important as genetic mutations behind the transition of a cell from normal to cancerous, and their manipulation holds great promise for cancer prevention, detection and therapy. In different types of cancer, a variety of epigenetic mechanisms can be perturbed, such as silencing of tumor suppressor genes and activation of oncogenes by altered CpG island methylation patterns, histone modifications and dysregulation of DNA binding proteins.
- Track 3-1Cancer genomics
- Track 3-2Epigenetic influence on genomic stability
- Track 3-3Moleculatr underpinnings of therapeutic targets
- Track 3-4Aberrant DNA methylation genes
- Track 3-5Tumor heterogeneity
Cancer metabolism refers to the alterations in cellular metabolism pathways that are evident in cancer cells compared with most normal tissue cells. Metabolic alterations in cancer cells are numerous and include aerobic glycolysis, reduced oxidative phosphorylation and the increased generation of biosynthetic intermediates needed for cell growth and proliferation.
It is widely accepted that chronic inflammation critically contributes to cancer. Immune tolerance in cancer mediates tumor escape from the immune system. Inflammation mediates tumor-induced tolerance. The induction and the maintenance of the chronic inflammatory response is a universal mechanism of immune tolerance.
Nanoparticles have been of significant interest over the last decade as they offer great benefits in drug delivery to overcome limitations present in case of conventional chemotherapy. They can not only be formed in a range of sizes (1-1000 nm) but also made by using a variety of materials including polymers, lipids, inorganic materials and biological materials. Using targeted nanoparticles to deliver chemotherapeutic agents in cancer therapy, offers many advantages to improve drug/gene delivery and to overcome many problems associated with conventional chemotherapy.
The normal treatment modalities are associated with severe side effects and high toxicity which in turn lead to low quality of life. This review encompasses novel strategies for more effective chemotherapeutic delivery aiming to generate better prognosis. Currently, cancer treatment is a highly dynamic field and significant advances are being made in the development of novel cancer treatment strategies. In contrast to conventional cancer therapeutics, novel approaches such as ligand or receptor based targeting, intracellular drug targeting, gene delivery, cancer stem cell therapy, magnetic drug targeting and ultrasound-mediated drug delivery, have added new modalities for cancer treatment.
- Track 7-1Cancer Epigenetics
- Track 7-2Molecular Profiling Techniques
- Track 7-3New Biologics & Vaccines
- Track 7-4Chemical Proteomics
- Track 7-5Combination Strategies in Immuno-oncology
- Track 7-6Novel Biomarker Discovery
Types of Cancer which are closely linked to certain behaviours are the easiest to prevent. Many complementary health approaches are also found to combat the risks associated with cancer like, for example, herbal and other dietary supplements, acupuncture, massage and yoga.
- Track 8-1Lifestyle changes
- Track 8-2Diet & Cancer
- Track 8-3Vaccinations
- Track 8-4Natural Therapy
- Track 8-5Psychological & Social Aspects
Cancer pharmacology plays a key role in drug development. In both the laboratory and the clinic, cancer pharmacology has had to adapt to the changing face of drug development by establishing experimental models and target orientated approaches.
Since its inception, the field of tumor virology has provided ground-breaking insights into the causes of human cancer. Tumor virologists additionally recognized that viruses could serve as powerful discovery tools, leading to revolutionary breakthroughs in the 1970s and 1980s that included the concept of the oncogene, the identification of the p53 tumor suppressor, and the function of the retinoblastoma tumor suppressor. This rich history promises that tumor virology will continue to contribute to our understanding of cancer and to the development of new therapeutic and preventive measures for this disease.
Tumor Immunology and Immunotherapy focuses on recent advances in understanding the range of immune responses towards cancer and how these can be modified and harnessed for prevention and therapeutics.
Malignancy has a differentiated nature in connection to the organ specificity. The essential focus is on heterogeneity, starting point, metastasis, angiogenesis and organ indicated systems in disease cells. There is a diverse spectrum of diseases, taking into account the area of tumor in the body organ. Organ-particular metastasis includes disease cell collaborations with the host micro-environment, including actuation of paracrine cytokine circles, change of the host cell synthesis, and modification of extracellular framework structures.
A cancer biomarker refers to a substance or process that is indicative of the presence of cancer in the body. A biomarker may be a molecule secreted by a tumor or a specific response of the body to the presence of cancer. Genetic, epigenetic, proteomic, glycomic, and imaging biomarkers can be used for cancer diagnosis, prognosis, and epidemiology. Ideally, such biomarkers can be assayed in non-invasively collected bio-fluids like blood or serum.
- Track 13-1Imaging Biomarkers
- Track 13-2Clinical Biomarkers
- Track 13-3Genetic Biomarkers
- Track 13-4Predictive Cancer Biomarkers
- Track 13-5Molecular Biomarkers
- Track 13-6Cell Free Biomarkers
Stem cell transplants are procedures that restore blood-forming stem cells in people who have had theirs destroyed by the very high doses of chemotherapy or radiation therapy that are used to treat certain cancers.
- Track 14-1Cancer Stem Cells
- Track 14-2Stem Cells and Tumors
- Track 14-3Stem Cell Transplantation
- Track 14-4Bone Marrow Transplantation
- Track 14-5Cord Blood Stem Cells and Cancer
- Track 14-6Stem Cell Research
Anti-Cancer agents in Medicinal Chemistry aim to cover all the latest and outstanding developments in medicinal chemistry and rational drug design for the discovery of anti-cancer agents. Anti-Cancer Agents in Medicinal Chemistry is an essential journal for every medicinal chemist who wishes to be kept informed and up-to-date with the latest and most important developments in cancer drug discovery.
Surgical oncology is a specialty that focuses on the surgical treatment of a variety of tumors. Ephraim McDowell did the first reported resection of an ovarian tumor in 1809, but as early as the 7th century, ancient Egyptians described techniques for removing breast tumors.
Cancer treatments today are likely to cause less physical deformity from surgery than a half-century ago, but are more complex and extend over a longer period of time. People today are often well informed about the details of their cancer diagnosis and prognosis, and are increasingly involved in shared decision-making regarding treatment. Although serious depression is not seen in the majority of cancer patients and survivors, many will experience treatment-related distress, fear of recurrence, changes in body image and sexuality, as well as physical toxicities that result from adjuvant therapy. It is important to identify the psychological and social concerns of cancer patients in the medical setting, and assisting them in obtaining appropriate psychosocial services.
Radiation oncology is a medical speciality that involves the controlled use of radiation to treat cancer either for cure, or to reduce pain and other symptoms caused by cancer. Radiation therapy (also called radiotherapy) is the term used to describe the actual treatment delivered by the radiation oncology team.
The word chemotherapy means drugs used for cancer treatment. It’s often shortened to “chemo.” Surgery and radiation therapy remove, kill, or damage cancer cells in a certain area, but chemo can work throughout the whole body. This means chemo can kill cancer cells that have spread (metastasized) to parts of the body far away from the original (primary) tumor.
Cancer diagnostics market is witnessing high growth due to increasing prevalence and incidences of several types of cancers. Major drivers for the global cancer diagnostic market are technologically advanced and increasing point-of-care diagnostics, cost-effective treatment modalities and personalized medicine. Additionally, increasing persistence to provide best-in-class healthcare services with high accuracy and efficiency towards patient is expected to fuel the global cancer diagnostics market across the globe.
Alternative cancer treatments may not play a direct role in curing the cancer, but they may help in coping up with the signs and symptoms caused by cancer and cancer treatments. CAM (Complementary and Alternative Medicine) is the term for medical products and practices that are not part of standard care.Integrating the best of evidence-based complementary and alternative cancer treatments with the treatments you receive from your doctor may help relieve many of the symptoms associated with cancer and its treatment.
Medical Oncology (MO) communicates the results of clinical and experimental research in oncology and hematology, particularly with experimental therapeutics in the field of immunotherapy and chemotherapy. It also provides state-of-the-art reviews on clinical and experimental therapies in oncology and hematology. Topics covered include immunobiology, pathogenesis and treatment of malignant tumors.
Carcinogenesis, also called oncogenesis or tumorigenesis, is the mechanism of formation of a cancer, where normal cells are transformed into cancer cells. The process is characterized by changes at the cellular, genetic, and epigenetic levels and abnormal cell division.
Genetic susceptibility plays a role in many types of cancer. Identifying the genes involved in susceptibility to cancer may have potential utility in risk management, leading to greater understanding of the biological pathways involved in cancer development, and elucidate how environmental factors exert their effects in combination with genetic variants.
As persistent infection with viruses, bacteria, or parasites is a predominant cause of human cancer, notably in low- and middle-income countries, Infections and Cancer Epidemiology contributes substantially to IARC′s mission of cancer prevention in the most vulnerable populations.
The Infections and Cancer Epidemiology Group (ICE) has estimated that approximately 2 million cancer cases worldwide can be attributed to infectious agents. Promoting human papillomavirus (HPV) vaccination and cervical screening programmes for the prevention of cervical cancer is an ICE priority. However, other associations between infectious agents and cancer require additional research and better standardized control measures.
Cancer treatments that target the specific changes, most often in proteins, that underlie the growth and development of cancer. Surgery, radiation therapy, and standard chemotherapy will continue to play an important role in treating cancer, but the emergence of targeted therapies and of immunotherapies,in the recent years, which harness the power of the immune system to fight cancer, have expanded the treatment options available to patients with certain types of cancer.
The Cancer Genetics and Genomics (CGG) Program serves to coordinate the research activities related to the study and understanding of cancer genomics, epigenetics, gene expression, model systems and host interactions. The CGG is at the forefront of applying 'omics' technologies that assess alterations in cancer genomes, epigenomes and transcriptomes, or techniques that are capable of editing the genome or epigenome of a model system. The program serves as the primary source of expertise for these aspects of cancer.
- Track 28-1Tumor cell proliferation
- Track 28-2Genetic Studies
- Track 28-3The Cancer Genome Atlas (TCGA)
- Track 28-4Genetic Tools
- Track 28-5Metabolic Technologies
- Track 28-6Data Interpretations
The field of computational oncology has forged a new relationship between the physical sciences and oncology to further advance research. By applying physics and mathematics to oncologic problems, new insights will emerge into the pathogenesis and treatment of malignancies. One major area of investigation in computational oncology centres around the acquisition and analysis of data, using improved computing hardware and software. Large databases of cellular pathways are being analyzed to understand the interrelationship amongst complex biological processes.
Oncogene amplifications have been shown in solid human cancers and they are often associated with progression of cancer. Defining oncogene amplification is useful since it is used as a prognostic marker in clinical oncology nowadays, especially v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (HER2) targeted agents are used in breast cancer patients with high level of HER2 overexpression as a therapeutic approach.