5th World Congress on Cancer Therapy
Sree Chitra Tirunal Institute for Medical Sciences and Technology, India
Lissy K. Krishnan focuses her research on development of various biotherapeutics from small pool human plasma meeting International regulatiory requirements for clinical use. Her approach to use various compositions of cell-specifi c fi brin matrix as an in vitro niche for human adult stem cell has resulted in their selection to homogenous population and differentiation into various cell types for use in regenerative medicine. She has also designed fi brin-based niche for in vivo delivery of partially differentiated cells for various cell-based therapy. She has developed two drug delivery systems using human plasma proteins; (i) albumin for systemic and (ii) fi brin for local curcumin delivery aiming at increasing bioavalability for cancer therapy. She also designed in vitro engineered cancer tissue using lung cancer cell and biodegradable scaffold to be used as model for testing anticancer effect of curcumin. She is the senior author of several peer reviewed publications, book chapters, conference proceedings, reviewed many manuscripts for various journals, serves in editorial boards, in project review committees of national funding agencies and is the primary inventor of national/International patents.