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Kakil Ibrahim Rasul

Kakil Ibrahim Rasul

National Center for Cancer Care and Research, Qatar

Title: Status of hepatocellular carcinoma in Gulf region

Biography

Biography: Kakil Ibrahim Rasul

Abstract

Hepatocellular carcinoma (HCC) is 6th common cancer in incidence and 3rd leading cause of death worldwide, Increasing incident in developing countries including the gulf coutries; it is hepatitis associated cirrhosis leading to HCC in our area.  Growing problem of NASH related Liver cirrhosis also is also rising in the Gulf region. HCC has a unique geographic distribution that is likely to be determined by specific etiologic factors. There is a distinctive difference in sex and age related occurrence of disease. In the Gulf region, there are contradicting data on the prevalence and death rates due to HCC. In this review we highlight some aspects of HCC specific to the Gulf region. A retrospective analysis of 150 patient’s data is presented, including demographic, epidemiological, aetiological disease status assessment with child Pugh criteria, modes of treatment and treatment related outcome. Hepatitis C virus (HCV) infection was the most common (45%) documented etiology, similar to Western European countries, followed by hepatitis B virus (HBV) infection in 27% of cases, alcoholic liver disease only in six patients (4%). Child-Pugh assessment was A in 33%, B in 37% and C in 30% of observed patients. Surgery (liver resection or transplantation) was performed in 12% and local ablation in 5% of cases. The others were treated by chemo-embolization in 17% and by systemic therapy with sorafenib in 13% of patients. Nearly half of the patients (53%) were in advanced stages and received palliative treatment.

In other part of the presentation, have started regular Multidisciplinary (MDT) meeting at our center (NCCCR) we good collaboration with intervention radiologist we have good improvement in our patient treatment outcome. Included some examples of case presentation 

To improve the outcome of treatment in HCC patients in the Gulf region, an effective and strategic screening program must be implemented for early diagnosis and clear multidisciplinary group working for the treatment to improve the outcome of this mostly fatal disease.