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14th Asia Pacific Oncologists Annual Meeting

Melbourne, Australia

Yong Zheng


Yong Zheng

Wuhan University, China

Biography

Yong Zheng is presently studying the mechanisms underlying these changes of epigenetic modification. He has his research interests in understanding the molecular mechanisms of tumorigenesis. He has identified the key stages during the spontaneous of rat mesenchymal stem cells and his previous study identified, for the first time, an Ezh2/H3K27me-independent and H3K9me enhanced aberrant DNA methylation of the p16 gene, which might be an epigenetic signature for MSC spontaneous transformation.

Abstract

Abstract : The inactivation of tumor suppressor genes by increased H3K9me3 drives spontaneous transformation of rat MSCs