9th Indo Global Summit on Cancer Therapy
A.T.Still University of Health Sciences, USA
Title: Is melanoma a hormone dependent cancer?
Biography: Pandurangan ramaraj
Melanoma is a dangerous form of skin cancer with higher mortality rate in males than in females, indicating a sex difference. Though acquisition of melanoma was hormone independent, but survival in melanoma was hormone dependent as shown by clinical studies. Moreover previous animal and cell culture studies showed the regulation of melanoma growth by various hormones. This raises the question whether melanoma is a hormone dependent cancer? Based on epidemiological SEER data, clinical studies, previous animal and cell culture experiments and our own cell culture studies on mouse and human melanoma cells, an attempt has been made to show the involvement of sex steroids in the survival of melanoma.