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7th Global Summit on Cancer Therapy

Dubai, UAE

Rola F. Jaafar

Rola F. Jaafar

National University of Ireland Galway, Ireland

Title: RIP2 enhances survival through NF-κB in Triple Negative Breast Cancer

Biography

Biography: Rola F. Jaafar

Abstract

RIP2 is receptor interacting protein kinase well known for its function in immunity and inflammation by activation of the NF- κB pathway. It was also reported to be involved in cell proliferation and cancer development and metastasis. Here we show role of RIP2 in triple negative breast cancer. RIP2 increased cell count and resistance to death induced by cytotoxic drugs in MDA-MB-231 cells through NF- κB activation in these cells.