5th World Congress on Cancer Therapy
Jayoti Vidyapeeth Women’s University, India
Title: Cancer therapy, a review on anti neoplastic agent
Biography: Juhi Tiwari
Neoplasm word derives from Greek word “Neos” means new and “Plasma” means formation. Cancer is a genetic disease that can occur in all types of body tissues. Neoplasm may be as leukaemia (Blood cancer) and lymphomas (cancer of lymphoid cells). Neoplasm may be benign or malignant. Benign tumour do not metastasise but malignant tumour do. A neoplasm is an abnormal mass of tissue , the growth of which exceeds and is uncoordinated with that of normal tissue and continues in the same manner aft er cessation of the stimuli which have initiated it. Th ere are various causes of cancer for example: exposure to carcinogenic hydrocarbons or excessive radiations, culture factors, occupational factors and heredity factors. A normal cell persist to genetic damage which leads to the somatic mutation results into the tumour formation and then vascularisation occurs around tumour which causes the invasiveness and fi nally leads into the metastasis. Incidences of tumour are age, sex, geographical, ethnic, environment, virus and radiation incidence. Cancer is more diffi cult to cure than any bacterial infection because of higher chances of reoccurrence. Chemotherapy aims to assess effi cacy and tolerability of the combination regimen. A vast range of anti neoplastic agent have been researched but still there is a need of safe and eff ective drug with no or minimal adverse eff ects. Th e chemotherapy is adversely aff ecting to bone marrow, intestine, hair follical, CNS, nephrotoxicity, hepatotoxicity, skin rashes, germinal tissue and miscellaneous eff ects. Some natural substance also possesses antineoplastic property. In conclusion, three modalities are commonly used today in combination to treat cancer, surgery, radio therapy and chemotherapy. Curing Cancer is obviously a tremendously complicated goal. Research and regulatory community needs to provide a better chemotherapies and radio modulating agents with signifi cantly improved indices. Hypercompetition for the fi nancial resources that are required to conduct science appears to suppress the creativity, cooperation, risk-taking, and original thinking required to make fundamental discoveries, unduly favoring low-risk research into small incremental advancements over innovative research that might discover radically new and dramatically improved therapy.