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A-Lien Lu-Chang

University of Maryland, USA

Biography

A-Lien Lu-Chang has completed her PhD from the University of North Carolina at Chapel Hill and has done her Post-doctoral studies from Duke University, School of Medicine with Paul Modrich (Nobel laureate in Chemistry in 2015). She is working as the Professor of Biochemistry and Molecular Biology at University of Maryland Medical School and a Member of University of Maryland Greenebaum Comprehensive Cancer Center. She has published more than 63 peer-reviewed papers in reputed journals, holds a patent, and has been serving as an Eeditorial Board Member for four journals. Her laboratory is currently studying the interplays among DNA repair, DNA replication, cell cycle checkpoint, transcription and chromatin remodeling. She investigates the impact of their co-ordination on telomere integrity and carcinogensis. Her team’s work highlights potential targets that can be exploited clinically for cancer therapies.

Abstract

Abstract : SIRT1 and Chk1 inhibition as novel therapeutic strategies in melanoma