42^nd World Cancer Conference

Cancer and Pharmacology

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Addressing a wide range of pharmacologic and oncologic concerns on both experimental and clinical levels Cancer Chemotherapy and Pharmacology is an eminent journal in the field. Chemotherapeutic drugs that selectively act on pathogenic microorganisms and malignant cells are essential tools in human and veterinary medicine. The successful development of such agents since the early days of Paul Ehrlich, Alexander Fleming and others, and in particularly of antibiotics, constitutes one of the most important therapeutic advances in the history of medicine. Chemotherapeutic drugs are continuously under development, to increase drug selectivity and reduce general toxicity, but also to overcome drug resistance that arises with increased frequency in target cells. A peer- reviewed innovative investigation   of methods to improve cancer therapy.  Includes more selective delivery of drugs, biologicals, radiopharmaceuticals, or other agents, and advances in delivery instrumentation and technology, with the aim of increasing efficacy of therapy and/or decreasing toxicity or improving convenience of therapy. Pharmacokinetics, sometimes described as what the body does to a drug, refers to the movement of drug into, though, and out of the body—the time course of its absorption Drug Absorption, bioavailability (see Drug Bioavailability), distribution Drug Distribution to Tissues, metabolism Drug Metabolism, and excretion  Drug Excretion. Pharmacodynamics, described as what a drug does to the body, involves receptor binding, post receptor effects, and chemical interactions. Drug pharmacokinetics determines the onset, duration, and intensity of a drug’s effect. Formulas relating these processes summarize the pharmacokinetic behaviour of most drugs Formulas Defining Basic Pharmacokinetic Parameters.